Tuesday, November 23, 2010
How nerve cells grow
Effects of Self-Efficacy on Exercise - Email study
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Luszczynska, A., & Tryburcy, M. (2008) Effects of a Self-Efficacy Intervention on Exercise: The Moderating Role of Diabetes and Cardiovascular Diseases. Applied Psychology, 57(4), 644-659. DOI: 10.1111/j.1464-0597.2008.00340.x Effects of a Self-Efficacy Intervention on Exercise: The Moderating Role of Diabetes and Cardiovascular Diseases
Conservative versus liberal brains.
Report explains declining school performance
The Brain: a Bottleneck of Processing
Wednesday, November 10, 2010
A common thread links multiple human cognitive disorders
How compassionate meditation can reduce stress
Can you train yourself to be compassionate? A new study says, yes. According to researchers at the University of Wisconsin, cultivating compassion and kindness through meditation affects brain regions that can make you more empathetic to other peoples' mental and emotional states.
According to Richard Davidson, the lead researcher, professor of psychiatry and psychology and director of the HeathEmotions Research Institute, who studied a group of Tibetan monks who were master meditators, they exhibited significant activity in the brain's insula, which is important in detecting emotions and monitoring responses such as heart rate and blood pressure. In addition the temporal parietal juncture area of the right brain, associated with processing empathy became very active. Davidson reported that these two areas of the brain, studied with an fMRI, underwent significant activation in the test subjects.
The researchers concluded that an individual's capacity to cultivate compassion which involves regulating thoughts and emotions, may be useful in preventing depression, and that self-compassion, which is a necessary first step in developing compassion for others can be developed through compassionate meditation.
In another study by researchers at Emory University's center for Collaborative and Contemplative Studies, researchers concluded that compassionate meditation improved individuals' responses to stress. They reported that the test subjects, practicing compassionate meditation, showed reductions in inflammation and distress in response to stressors. This study reflects numerous studies which show that meditation is an effective method for controlling high blood pressure.
Together these two studies demonstrate that practicing compassionate meditation can be beneficial both to the individual and in relationships with others.
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Are We In Control of Our Own Decisions?
http://www.ted.com/talks/lang/eng/dan_ariely_asks_are_we_in_control_of_our_own_decisions.html
How to Relax Effectively with Progressive Muscle Relaxation
Progressive Muscle Relaxation
A no-nonsense video that combines Progressive Muscle Relaxation (PMR) narration with ambient, peaceful images. Promotes relaxation and sleep. A good coping technique, proven effective for stress and anxiety.
Meditation and health: Why do we tend to look toward the East?
Research demonstrates that meditation is good for our body, mind, and spirit. Yet we tend to only look towards the East and ignore the West when it comes to learning, practicing, and valuing meditative skills. This is a big mistake.
All of the religious and spiritual traditions offer thoughtful and effective contemplative and meditative practices and techniques. Mindfulness meditation, associated with the Buddhist tradition, is the approach that has gotten a lot of attention in recent years and perhaps has been the most successfully integrated into secular mental and physical health care. Practitioners such as Dr. Jon Kabat-Zinn from the University of Massachusetts Medical Center have helped to popularize this form of meditation and secularize it so that it is acceptable to both professionals and clients alike, regardless of religious tradition or involvement.
Mindfulness meditation is an excellent example of how a particular religiously based technique can be adapted to help others when it is in a form that is both understandable and acceptable to people who have no particular religious or spiritual affiliations. Clients can use the principles and techniques of this form of meditation to lower stress, improve their psychological and physical health, and ultimately improve the quality of their lives. The same is true for yoga. Yoga studios can be found throughout the United States and even in shopping and strip malls. Yoga is a complative and meditative practice associated with the Hindu tradition but has often been secularized to the point that it can feel like an exercise class. The remarkable success of mindfulness meditation and yoga in popular and professional practice underscores the interest in Eastern approaches to meditation and contemplative practices.
Curiously, most people seem to believe that meditation techniques are found only in the Eastern traditions and thus focus on approaches such as yoga, Taoism, prana, chi, Buddhism, Zen, mindfulness, and so forth. Many completely ignore meditative traditions from the Christian (e.g., centering prayer, the spiritual exercises of St. Ignatius), Jewish (e.g., Hasidic and Kabbalistic dillug and tzeruf approaches), Muslim (e.g., Sufism's zikr approach), and other Western traditions. Perhaps the Western traditions haven't done as well in promoting their meditative techniques.
Sadly, many conclude that Eastern traditions alone (especially those from India, Japan, and China) offer anything of value when it comes to meditation.
This is problematic because 85 percent of Americans identify themselves as Christian, 2 percent as Jewish, and about 3 percent as Muslim; thus about 90 percent of Americans identify with a Western religious tradition according to Gallup polling. Many feel that they have to abandon their tradition to secure meditative benefits or are fearful of trying meditative practices since they believe that they are from a tradition different from their own.
While almost anyone can learn from and certainly benefit from Eastern approaches, it seems reasonable to include Western approaches too. We should look to the West as well as to the East to learn and use meditative approaches. In doing so, we are likely to enhance our physical and mental health.
Doing the right thing for our body, mind, and spirit includes using meditative and contemplative practices...from the East or from the West.
"Recent Findings Don't Prove there's a Ghost in the Machine (Sorry Saletan)
On Tuesday, William Saletan at Slate posed the same question. Bouncing off recent evidence that some supposedly vegetative patients are in fact still able to think, Saletan writes, 'Human minds stripped of every other power can still control one last organ--the brain.'
Huh?
Every neuroscientist I've talked to would read this as a tautology: "the brain controls the brain." Given the gazillions of feedback circuits in the brain, that's a given. Reading further, though, Saletan clearly has something else in mind:
We think of the brain as its own master, controlling or fabricating the mind ... If the brain controls the mind this way, then brain scanning seems like mind reading ... It's fun to spin out these neuro-determinist theories and mind-reading fantasties. But the reality of the European scans is much more interesting. They don't show the brain controlling the mind ... The scans show the opposite: the mind operating the brain.'
Evidence Mind is Master
As I've already mentioned above, the paragraph quoted above is nonsensical in modern scientific theory, and I'll get back to why. But before that, what evidence is Saletan looking at?
In the study he's talking about, neuroscientists examined 54 patients who show limited or no awareness and no ability to communicate. Patients brains were scanned while they were asked to think of motor activities (swinging a tennis racket) or navigation activities (moving around one's home town). 5 of the 54 were able to do this. They also tried to ask the patients yes-no questions. If the answer was 'yes', the patient was to think about swinging a tennis racket; if 'no', moving around one's home town. One patient was able to do this successfully.
Note that the brain scans couldn't see the patient deciding 'yes' or 'no' -- actually, they couldn't see the patient deciding at all. This seems to be why Saletan thinks this is evidence of an invisible will controlling the physical brain: 'On the tablet of your brain, you can write whatever answer you want.'
The Mistake
The biggest problem with this reasoning is a misunderstanding of the method the scientists used. FMRI detects very, very small signals in the brain. The technology tracks changes in blood oxygenation levels, which correlates with local brain activity (though not perfectly). A very large change is on the order of 1%. For more complicated thoughts, effect sizes of 0.5% or even 0.1% are typical. Meanwhile, blood oxygen levels fluctuate a good deal for reasons of their own. This low signal-to-noise ratio means that you usually need dozens of trials: have the person think the same thoughts over and over again and average across all the trials. In the fMRI lab I worked in previously, the typical experiment took 2 hours. Some labs take even longer.
To use fMRI for meaningful communication between a paralyzed person and their doctors, you need to be able to detect the response to an individual question. Even if we knew were to look in the brain for 'yes' or 'no' answers -- and last I heard we didn't, but things change quickly -- its unlikely we could hear this whispering over the general tumult in the brain. The patients needed to shout at the top of their lungs. It happens that physical imagery produces very nice signals (I know less about navigation, but presumably it does, too, or the researchers wouldn't have used it).
Thus, the focus on visual imagery rather than more direct 'mind-reading' was simply an issue of technology.
Dualism
The more subtle issue is that Saletan takes dualism as a starting point: the mind and brain are separate entities. Thus, it makes sense to ask which controls the other. He seems to understand modern science as saying the brain controls the mind.
This is not the way scientists currently approach the problem -- or, at least, not any I know. The starting assumption is that the mind and brain are two ways of describing the same thing. Asking whether the mind can control the brain makes as much sense as asking whether the Senate controls the senators or senators control the Senate. Talking about the Senate doing something is just another way of talking about some set of senators doing something.
Of course, modern science could be wrong about the mind. Maybe there is a non-material mind separate from the brain. However, the theory that the mind is the brain has been enormously productive. Without it, it is extremely difficult to explain just about anything in neuroscience. Why does brain trauma lead to amnesia, if memories aren't part of the brain? Why can strokes leave people able to see but unaware that they can see?
Descartes' Error
A major problem with talking about the mind and brain is that we clearly conceptualize of them differently. One of the most exciting areas of cognitive science in the last couple decades has looked at mind perception. It appears humans are so constructed that we are good at detecting minds. We actually over-detect minds, otherwise puppet shows wouldn't work (we at least half believe the puppets are actually thinking and acting). Part of our concept of mind is that it is non-physical but controls physical bodies. While our concept of mind appears to develop during early childhood, the fact that almost all humans end up with a similar concept suggests that either the concept or the propensity to develop it is innate.
Descartes, who produced probably the most famous defense of dualism, thought the fact that he had the concept of God proved that God exists (his reasoning: how can an imperfect being have the thought of a perfect being, unless the perfect being put that thought there?). Most people would agree, however, that just because you have a concept doesn't mean the thing the concept refers to exists. I, for instance, have the concept of cylons, but I don't expect to run into any.
Thus, even as science becomes better and better at explaining how a physical entity like the brain gives rise to our perceptions, our experience of existing and thinking, the unity of mind and brain won't necessarily make any more intuitive sense. This is similar to the problem with quantum physics: we have plenty of scientific evidence that something can be both a wave and a particle simultaneously, and many scientists work these theories with great dexterity. But I doubt anyone really has a clear conception of a wave/particle. I certainly don't, despite a semester of quantum mechanics in college. We just weren't set up to think that way.
For this reason, I expect we'll continue to read articles like Saletan's long in the future. This is unfortunate, as neuroscience is becoming an increasingly important part of our lives and society, in a way quantum physics has yet to do. Consider, for instance, insanity pleas in the criminal justice system, lie detectors, and so on.
Quantum Psychology?
The author, Riccardo Franco, introduces a parameter that does doesn’t have any foundation in the phenomena it is trying to explain, nor is it shown to aid in [...]...
Franco, R. (2009) The conjunction fallacy and interference effects. Journal of Mathematical Psychology, 53(5), 415-422. DOI: 10.1016/j.jmp.2009.02.002 The conjunction fallacy and interference effects
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Sparking Creativity in the Workplace
Admit it. When do you get your best ideas? When you're sitting at your desk striving for an answer, or when you're doing something off-task like driving, walking, or puttering around the house?
On the surface, daydreaming seems like the antithesis of 'work,' yet it's truly at the core of our most important type of productivity--creative problem-solving. That's why some of the most innovative companies in the world feature programs that give key employees the time and space to think creatively, i.e. daydream--Google offers a 20% program, 3M has a 15% program, and Gore & Associates (Gore-Tex, etc.) features 'dabble time.' All three companies credit these programs as the source of their most successful products.
While many of us can see the relationship between daydreaming and creativity in the arts and even science, we've been slower to come around to its usefulness in business. Say the word 'visionary' however, and we understand how having a vision--a mental image or plan--can help someone start a breakthrough company or service.
Yes, I know. All the work and focus must follow to have an idea come to fruition. But the original idea and the motivation to fulfill that idea are birthed in a daydreaming state, and we do our most creative problem-solving when the mind wanders. While daydreaming, we can:
1) Envision-model and simulate in our mind's eye
2) Think uncensored thoughts-necessary for originality
3) Free associate-make random connections and come up with novel solutions
4) Tap into the most complex regions of the brain
Why Encourage Creativity at Work?
The new economy demands it. Global competition and the fast pace of technological change have left many of us scrambling. In addition, we've become much more of a thought-based economy than a widget-based one, and such an economy has a voracious appetite for ideas and innovation.
In addition, no one can rest on his or her laurels anymore. It used to be people apprenticed their way up the ladder, eventually becoming the wise elder of their trade. Now we all have to scramble just to stay relevant. Those who actually want to be ahead of the curve are going to have to be visionary. Those businesses or individuals lost only in the tunnel vision of task will be left behind.
Encouraging creativity is also good for attracting and retaining quality employees, always an issue even in this bad economy. Encouraging your employees to think creatively also helps to ensure that ideas stay under your roof, instead of having them take their ideas somewhere else or start a competing business.
How to Spark Creativity at Work
• Tell people you want their ideas then give them some amount of time and space to think creatively (i.e. daydream!). Instead of fearing that you're losing an employee's clocked-in time to creative thinking, look at it from another angle--you are gaining much wider access to a person's creative energies by encouraging them to explore ideas whenever the inspiration strikes, which is often outside of prescribed work hours. Offering up as little as thirty minutes of work time a week for exploratory thought could send the message that creativity is valued, no matter when, where, or how ideas are conceived.
• Ask 'what if' questions and encourage speculative thinking.
• Accept risk and a certain amount of failure. I believe it was Edison who said 'to have one good idea, have a lot of them.'
• Provide a forum for idea sharing and give feedback.
• Get rid of your old-school ideas about daydreaming, and start doing it. Go ahead--I'm giving you permission. Among the many benefits of daydreaming-it's fun, and we can all use some of that.
© Amy Fries
image: istock.com/PeskyMonkey
For more information, check out
Daydreams at Work: Wake Up Your Creative Powers
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Evolutionary origins of religion: weak relation to morality
Ilkka Pyysiäinen, & Marc Hauser. (2010) The origins of religion: evolved adaptation or by-product?. Trends in Cognitive Sciences. info:/10.1016/j.tics.2009.12.007
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Why The Media Seems Biased When You Care About The Issue
The media may well be biased, in fact it would be a miracle if it were permanently and perfectly balanced, that isn't what this post is about.
Instead this is about how you and I perceive the presence or absence of bias in the media.
This study, conducted in the 1980s, helps to explain a lot of the heat and light that gets produced by those commenting on media bias across the political spectrum, including the remarkably vitriolic outpourings often seen in the comment sections of newspaper websites and across the internet.
The Beirut massacre
Robert P. Vallone and colleagues from Stanford University invited 144 Stanford undergrads who held a variety of views on the continuing Arab-Israeli conflict to watch some of the news coverage of the Beirut massacre (Vallone et al., 1985). The Beirut massacre was the killing of between 328 and 3,500 Palestinian and Lebanese civilians by Lebanese militia forces in September 1982.
At the time the story received huge media coverage around the world with much speculation about whether Israeli forces had allowed it to happen (a subsequent commission held the Israeli government indirectly responsible).
Some of the participants recruited for the study were moderate in their initial views, others were specifically recruited from both the pro-Arab and pro-Israeli student associations. Each was asked for their views about the conflict, its history and where their sympathies lay. Here's what they found:
- 68 were pro-Israeli,
- 27 were pro-Arab,
- 49 had mixed feelings.
All the participants then watched a series of news segments taken from US networks (NBC, ABC and CBS). Afterwards they were asked to rate whether overall it was for or against Israel. They used a scale of 1 (heavy pro-Arab bias) to 9 (heavy pro-Israel bias) where a rating of 5 was fair and impartial.
The results
Here are the average ratings for the news coverage from each group:
- Pro-Israeli: 2.9 (perceived a marked pro-Arab bias)
- Neutral: 3.8 (perceived a slight pro-Arab bias)
- Pro-Arab: 6.7 (perceived a marked pro-Israeli bias)
As you can see the pro-Israeli participants thought the news reports were biased against Israel while the pro-Arab participants thought the news reports were biased against Arabs. This is impressive because everyone was watching exactly the same news reports. Even more surprising was that each thought that when someone neutral saw the coverage, it would persuade them to side with the opposite position.
Notice that those who claimed to be neutral thought the coverage had a slight pro-Arab bias. This could be a hint of actual media bias or could be just an unacknowledged bias in those initially declaring themselves neutral.
Causes of the hostile media phenomenon
The study demonstrates what the authors call the 'hostile media phenomenon': people's tendency to view news coverage about which they hold strong beliefs as biased against their own position.
There were two mechanisms at work here:
- The truth is black and white: partisans generally thought that the truth about the Arab-Israeli debate was black and white. Any hint of shades of grey in the news reports was interpreted by partisans as bias towards the other side. In other words: any balanced report will seem biased to partisan viewers.
- The news report was too grey: as well as thinking the Arab-Israeli issue was either black or white, partisans also perceived that the specific news report they watched was too grey.
Put simply: when we care about an issue, we tend not to notice all the points we agree with, and focus on the ones we don't.
Admitting bias
Whether the news actually is biased in one particular outlet about an issue that you care about can be very hard to quantify.
What we can say from this study is that people who care about a particular issue will tend to find media bias everywhere, whether or not it really exists. Not only that but they are unlikely to admit this fact to themselves since this study, amongst others, also shows how remarkably resistant we are to admitting to our own biases, even when they are categorically demonstrated to us.
» From PsyBlog's archives: 7 Reasons Leaders Fail.
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Religiosity tied to socioeconomic status.
The Science News Focus story 'On the origin of religion' (E. Culotta, 6 November 2009, p. 784) did not incorporate the growing body of psychosociological research that is revealing the crucial role of socioeconomics in the origin and popularity of religion, as well as in creationism (1–6). Some hunter-gatherers have minimal religion (7), and those who do not believe in the gods and an afterlife have spontaneously expanded in prosperous democracies until they are the majority in some nations, such as France, Sweden, and Denmark (1, 3, 4). Because religion is not universal, as implied in the News Focus article, serious religiosity cannot be the strongly genetically programmed result of major selective evolutionary pressures such as social cohesion (8).
In modern nations, nonreligion and the acceptance of evolution become popular when the middle class majority feels sufficiently secure and safe, thanks to low income inequality, universal health care, job and retirement security, and low rates of lethal crime; this has occurred to greater and lesser degrees in most first-world countries, from Japan to Scandinavia (1–6). Religion thrives when the majority seek the aid and protection of supernatural powers because they are impoverished, as in the third- and second-world countries or, in the case of the United States (the most religious and creationist first-world country), because the majority of Americans fear losing their middle-class status as a result of limited government support, high levels of social pathology, and intense economic competition and income disparity (1–6). Prosperous modernity is proving to be the nemesis of religion.
References
* 1. G. Paul, Evol. Psychol. 7, 398 (2009); www.epjournal.net/filestore/EP07398441_c.pdf.
* 2. T. Rees, J. Relig. Soc. 11 (2009); moses.creighton.edu/JRS/2009/2009-17.html.
* 3. P. Zuckerman, Soc. Compass 3, 949 (2009). [CrossRef]
* 4. P. Norris, R. Inghelart, Sacred and Secular (Cambridge Univ. Press, Cambridge, 2004).
* 5. A. Gill, E. Lundsgaarde, Rational. Soc. 16, 399 (2004). [CrossRef]
* 6. S. Verweii, P. Ester, R. Naata, J. Sci. Study Relig. 36, 309 (1997). [CrossRef] [Web of Science]
* 7. F. Marlowe, in Ethnicity, Hunter-Gatherers, and the 'Other,' S. Kent , Ed. (Smithsonian Institute Press, Washington, DC, 2002), pp. 247–281.
* 8. C. N. Wade, The Faith Instinct (Penguin, New York, 2009).
How framing affects our thought processes
Hardisty, D., Johnson, E., & Weber, E. (2009) A Dirty Word or a Dirty World?: Attribute Framing, Political Affiliation, and Query Theory. Psychological Science, 21(1), 86-92. DOI: 10.1177/0956797609355572 A Dirty Word or a Dirty World?: Attribute Framing, Political Affiliation, and Query Theory
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how does language shape the way we think?
The last example that language shapes the way we think is the use of grammatical gender. In spanish and other Romantic languages, nouns are either masculine or feminine. What it means for a language to have grammatical gender is that words belonging to different genders get treated differently grammatically and words belonging to the same grammatical gender get treated the same grammatically. Languages can require speakers to change pronouns, adjective and verb endings, possessives, numerals, and so on, depending on the noun's gender. In a study, German and Spanish speakers were asked to describe objects having opposite gender assignments between the two different languages. The descriptions they gave differed in a way predicted by grammatical gender. For example, when asked to describe a 'key' — a word that is masculine in German and feminine in Spanish — the German speakers were more likely to use words like 'hard,' 'heavy,' 'jagged,' 'metal,' 'serrated,' and 'useful,' whereas Spanish speakers were more likely to say 'golden,' 'intricate,' 'little,' 'lovely,' 'shiny,' and 'tiny.' 'In fact, you don't even need to go into the lab to see these effects of language; you can see them with your own eyes in an art gallery. Look at some famous examples of personification in art — the ways in which abstract entities such as death, sin, victory, or time are given human form. How does an artist decide whether death, say, or time should be painted as a man or a woman? It turns out that in 85 percent of such personifications, whether a male or female figure is chosen is predicted by the grammatical gender of the word in the artist's native language. So, for example, German painters are more likely to paint death as a man, whereas Russian painters are more likely to paint death as a woman.' (taken from the article.)
The fact the use of different languages alters the way we perceive the world, and the objects we look at and changes the perception of space is amazing. The way i am thinking about where i am sitting right now, typing this response would be different to an australian or someone from spain. From the perception of space, time and even nouns, languages changes the way we think. These studies show that linguistic processes effect even down to the most fundamental thought processes which unconsciously shapes our brain altering perception. Language is important to how we all deal with experience with each other and how we view the world.
Bonuses generate more heat than light
The engaging behavioural economist Dan Ariely has just become a columnist for Wired UK and in his first article he describes how the promise of performance-related pay often backfires leading people to do more but perform worse.
To see the effect of bonuses on performance, Nina Mazar (assistant professor of marketing, Toronto University), Uri Gneezy (professor of economics and strategy, University of California, San Diego), George Loewenstein (professor of economics, Carnegie Mellon, Pennsylvania) and I conducted three experiments. In one we gave subjects tasks that demanded attention, memory, concentration and creativity. We asked them, for example, to assemble puzzles and to play memory games while throwing tennis balls at a target. We promised about a third of them one day's pay if they performed well. Another third were promised two weeks' pay. The last third could earn a full five months' pay. (Before you ask where you can participate in our experiments, I should tell you that we ran this study in India, where the cost of living is relatively low.)
What happened? The low-and medium-bonus groups performed the same. The big-bonus group performed worst of all.
Link to 'Bonuses boost activity, not quality' in Wired UK.
Full disclosure: I'm a contributing editor to Wired UK. I have never received a bonus in my life, but if I do, I hope to spend it beautiful on women and fast cars, although, in reality, I will probably buy a laptop.
"Comatose Communications - PVS Patient Brain Scans Show Potential of Awareness (VIDEO)
Brain Scanning Software Showdown
Unfortunately, no. You still need to do the analysis, and this is often the trickiest stage. The raw data produced during an fMRI experiment are meaningless - in most cases, each scan will give you a few hundred almost-identical grey pictures of the person's brain. Making sense of them requires some complex statistics.
The very first step is choosing which software to use. Just as some people swear by Firefox while others prefer Internet Explorer for browsing the web, neuroscientists have various options to choose from in terms of image analysis software. Everyone's got a favourite. In Britain, the most popular are FSL (developed at Oxford) and SPM (London), while in the USA BrainVoyager sees a lot of use.
These three all do pretty much the same thing, give or take a few minor technical differences, so which one you use ultimately makes little difference. But just as there's more than one way to skin a cat, there's more than one way to analyze a brain. A paper from Fusar-Poli et al compares the results you get with SPM to the results obtained using XBAM, a program which uses a quite different statistical approach.
Here's what happened, according to SPM, when 15 volunteers looked at pictures of faces expressing the emotion of fear, and their brain activity was compared to when they were just looking at a boring 'X' on the screen (I think - either that it's compared to looking at neutral faces; the paper isn't clear, but given the size of the blobs I doubt it's that.)
Now, here's what happens if you analyze exactly the same data using XBAM, setting the statistical threshold at the same level (i.e. in theory being no more or less 'strict') -
Analysis using both programs revealed that during the processing of emotional faces, as compared to the baseline stimulus, there was an increased activation in the visual areas (occipital, fusiform and lingual gyri), in the cerebellum, in the parietal cortex [etc] ... Conversely, the temporal regions, insula and putamen were found to be activated using the XBAM analysis software only.
This begs two questions: why the difference, and which way is right?
The difference must be a product of the different methods used. By default SPM uses a technique called statistical parametric mapping (hence the name) based on the assumption of normality. FSL and BrainVoyager do too. XBAM, on the other hand, differs from more orthodox software in a number of other ways; the most basic difference is that it uses non-parametric statistics but this document lists no less than five major innovations (Edit: although see the comments below this post)
- 'not to assume normality but to use permutation testing to construct the null distribution used to make inference about the probability of an 'activation' under the null hypothesis.'
- 'recognizing the existence of correlation in the residuals after fitting a statistical model to the data.'
- using 'a mixed effects analysis of group level fMRI data by taking into account both intra and inter subject variances.'
- using '3D cluster level statistics based on cluster mass (the sum of all the statistical values in the cluster) rather than cluster area (number of voxels).'
- using 'a wavelet-based time series permutation approach that permitted the handling of complex noise processes in fMRI data rather than simple stationary autocorrelation.'
The biggest question, though, is: should we all be using XBAM? Is it 'better' than SPM? This is where things get tricky. The truth is that there's no right way to statistically analyze any data, let alone fMRI data. There are lots of wrong ways, but even if you avoid making any mistakes, there are still various options as to which statistical methods to use, and which method you use depends on which assumptions you're making. XBAM rests of different assumptions from SPM.
Whether XBAM's assumptions are more appropriate than those of SPM is a difficult question. The people who wrote XBAM presumably think so, and they're very smart people. But so are the people who wrote SPM. The point is, it's a very complex issue, the mathematical details of which go far beyond the understanding of most fMRI users (myself included).
My worry about this paper is that the average Joe Neuroscientist will decide that, because XBAM produces more activation than SPM, it must be 'better'. The authors are careful not to say this, but for fMRI researchers working in the publish-or-perish world of modern science, and whose greatest fear is that they'll run an analysis and end up with no blobs at all, the temptation to think 'the more blobs the merrier' is a powerful one.
What Zaps a High Achiever’s Performance Lights a Low Achiever’s Fire
High achievers do many things well, particularly when they’re convinced that excellence requires their utmost performance. Low achievers, however, have a hard time getting motivated and often find themselves coughing in the dust of the high achievers’ hustle.
But like so many generalizations, this one has a limit.
A new study in the Journal of Personality and Social Psychology uncovered a variable that knocks this scenario on its head, and it has everything to do with what makes low achievers tick.
Researchers conducted multiple studies to evaluate how participants’ attitudes toward achievement influenced their performance. In one study, participants were “primed” with high-achievement words (related to winning, excellence, etc.) flashed on a computer screen. Each word appeared only for an instant, too fast for conscious deliberation. Participants with high-achievement motivation performed significantly better on tasks after being primed with the words than those with low-achievement motivation.
In another study, participants completing a verbal proficiency task (word-search puzzles) were interrupted, and then given a choice to either resume the task or switch to a task they perceived as more enjoyable. Those with high-achievement motivation were significantly more likely to return to the verbal task than the low achievers.
The results of those studies are predictable and buttress what we generally know about high and low achievers. But the final study was different. Participants were primed with high-achievement words (e.g. excel, compete, win) and then asked to complete a word-search puzzle. But instead of describing the task as a serious test of verbal proficiency, the researchers called it “fun.”
The results: participants with high-achievement motivation did significantly worse on the task than low achievers.
The study authors believe that when high achievers are primed to achieve excellence, the idea that a task is “fun” undercuts their desire to excel. If something is enjoyable and fun, how could it possibly be a credible gauge of achievement?
Conversely, low achievers who are similarly primed with achievement words perceive a “fun” task as worthwhile. Not only is their motivation to perform improved, so is their ability.
This intriguing twist says much about why one-size-fits-all educational strategies so often fail. For students motivated to achieve excellence, making tasks entertaining may actually undermine their performance. Likewise, for those not normally motivated to achieve, describing a task as urgent and serious yields the predictable result.
It also sheds light on the “lazy genius” phenomenon. Everyone has known someone who is remarkably intelligent but gets mediocre grades and doesn’t seem to care. Clearly, low-achievers are not necessarily less intelligent or less capable than high-achievers; instead, they just don’t respond well to status quo motivational cues. A jolt of enjoyment could turn that around.
Hart W, & AlbarracÃn D (2009). The effects of chronic achievement motivation and achievement primes on the activation of achievement and fun goals. Journal of personality and social psychology, 97 (6), 1129-41 PMID: 19968423
Newsweek: Do Antidepressants Work? For Many People, YES!
I admire Newsweek writer Sharon Begley’s work … especially when she explains ways we can try to rewire our brain. But I found last week’s cover story irresponsible. If, for no other reason, than its title and subtitle: “The Depressing News About Antidepressants: Studies Suggest That the Popular Drugs Are No More Effective Than a Placebo. In Fact, They May Be Worse.”
Then I may as well kill myself.
That’s how I would have read the article four years ago, before I started questioning all the information available today on mood disorders and drug treatment, before I started working with a physician from Johns Hopkins who could help me tease out the hope from articles like this, so I wasn’t tempted to take my life upon reading there was no way out of the darkness.
In fact, on the way to my consultation at the Johns Hopkins Mood Disorders Clinic, I read a similar article in O magazine: a compilation of interviews with folks about how antidepressants zap creativity, dull emotions, destroy creativity, flatten libidos, and a list of other things. Shaking with anxiety and tears coming down my face, I almost told Eric to turn around, that I was foolish to think that there was hope for me, that I was a lost case, and that, if the article was right, I would only be making matters worse.
Thank God I threw the article into the backseat and went on with my consultation.
I don’t know why the main body of research behind the article is so surprising: antidepressants work better for those with severe depression than for those who suffer from mild to moderate depression. Can’t we say that as part of the subtitle, to help out the folks who are banking on medical intervention to lighten their crushing and burdensome load?
I’ve always maintained that if a person has mild to moderate depression, then he should start with his diet, sleep, exercise. Try yoga or some acupuncture sessions. In many cases, that’s enough!
For folks like me, though, who are/were hanging on to life by a very thin and fraying thread, antidepressants can save lives. They have certainly given me back my life. I know that. Because I tried absolutely everything else I could to make the death thoughts go away, and they continued to stalk me until I found the right medication combination. Now, instead of putting 95 percent of my energy into NOT taking my life, I can invest it into helping others not take their own lives and to giving back. Which is why I think magazines like Newsweek, with so much power over the information we process, should be more careful than to say: Sorry folks, for those of you so desperate, well, you may as well give up and take a gun to your head.
John Grohol always provides a number of insights to media stories with unfortunate sticking power. In a recent post, “Are Antidepressants Really That Ineffective?” he writes:
Newsweek’s Sharon Begley has a lengthy article discussing the growing body of evidence that calls into question decades’ worth of prescriptions. It seems to be journalists’ favorite “go to” story now in mental health, because there’s a black-and-white controversy — do antidepressants work or don’t they?
People mistakenly believe that one type of research is somehow superior to another form of research. However, data is data and research is research. All things being equal, if it’s done in as objective a manner a human being can do it, then it’s all good and informative. A study conducted 20 years ago is just as valid today, as long as the design of the study was solid and unbiased. And a single-case experimental design, while not very generalizable, can still lead — and has led — to valuable insights into human behavior.
So I get a little concerned when we do give more weight to the most recent study, or the most recent meta-analysis. They have their place, but their place is in context — understanding the body of research as a whole. (Because meta-analyses never take into account the entire body of research on a drug or topic — they always have inclusion and exclusion criteria, criteria that can directly impact the results they find.)
To see another article about this issue go ’round and ’round the bend with both sides, but not really bringing anything new to the discussion, is a little frustrating. I think it’s pretty obvious that if a drug was supposed to help people, but didn’t, people would stop taking it and doctors would eventually stop prescribing it. Since it’s unethical to prescribe placebos to patients outside of a research study, what choice do doctors and patients have — the drug works. (Well, not always, of course, but in many people who take it, and who keep trying a different antidepressant if the first one doesn’t work, according to the results of the STAR*D study.)
In other words, can we please get back to a forest view of mood disorders so that, while we’re busy analyzing the lady bug on the bark of a tree, we don’t miss the guy with one leg off the bridge? Antidepressants aren’t fool proof. Unfortunately. Sometimes you have to try a few before you feel relief, and for some people (especially those who suffer from mild to moderate depression, that can benefit more from other kinds of therapies), SSRIs might not work at all.
But let me say this loud and clear: There is hope. Depression is treatable. It is, as William Sytron wrote in his classic, “Darkness Visible,” “conquerable.” And much of that has to do with the drugs that are available today.
Multitaskers....don't.
A study found that the people that multitask the most are the least effective at it. It would be interesting to evaluate ADHD symptoms in the study sample, and see how it correlates with multitasking effectiveness.
In the MSNBC.com article, Clifford Nass Ph.D. said,
'Is multitasking causing them to be lousy at multitasking, or is their lousiness at multitasking causing them to be multitaskers?' Nass wondered. 'Is it born or learned?'
Read the article here:
"ASSOCIATIVE MEMORIES:
ASSOCIATIVE MEMORIES: “AI researchers in the 80s ran into a problem: the more their systems knew, the slower they ran. Whereas we know that people who learn more tend to get faster (and better in other ways) at whatever it is they’re doing.”
Moms influence how children develop advanced cognitive functions
New Studies Reveal That Schizophrenia Isn't Just A Mental Illness [Medicine]
Researchers at the University of Cambridge have discovered that the effects of schizophrenia appear to extend beyond the brain. And now there's talk of a blood test to diagnose schizophrenia being rolled out within a year.
Because schizophrenia is a psychiatric disorder, it was previously believed that the signs of the illness would be contained only within the brain. However, the team at the Cambridge Institute for Psychiatric Research, led by Sabine Bahn, has identified genetic markers of the disorder in cell division, the immune system, and glucose metabolism. They have found that one of the best peripheral indicators of schizophrenia is a systemic problem in protein expression in the skin cells of the patient's arms.
According to Bahn:
'It's clear that schizophrenia has a very strong genetic component. Most genes are not used only in the brain. If there is an underlying abnormality at the genetic level that leads to pathology in the brain, the assumption can be made that there should also be dysregulation in the peripheral system. It may not lead to pathology, but it may reflect the pathology in the brain.'
The researchers estimate that about 40% of the changes seen in the brains of schizophrenics can be observed elsewhere in their bodies. Although Bahn originally focused on skin cells, she has now shifted to immune cells, which are closer in function to the neurons of the brain. She hopes this will better clarify just how the genetic and psychiatric components of schizophrenia interact.
The main caveat with this study that independent researchers have raised is that these peripheral indicators might not do much to improve our understanding of the root causes of the disorder. However, even if the theoretical implications of this work proves somewhat limited, Bahn hopes the practical implications will be enormous:
Bahn nevertheless believes peripheral-cell-based diagnostics will be useful. She and her coworkers have identified schizophrenia biomarkers in serum, and working with the company Rules-Based Medicine, located in Austin, Texas, and Lake Placid, N.Y., she expects that a serum-based test to aid in the diagnosis of schizophrenia will be launched sometime this year.
'We've identified a signature of numerous protein biomarkers, which give a very high sensitivity and specificity,' Bahn says. 'We've looked at hundreds of samples from patients and controls and other disorders that are related to schizophrenia.'
Currently, it can take several years to definitively diagnose a patient as schizophrenic. These new tests could reduce that figure dramatically. A schizophrenic's long-term well-being can be substantially improved with early detection of the condition.
Brain Scan Shows Vegetative Patient Responding To Yes-or-No Questions

The study covered 54 patients in a supposed vegetative state. Of those 54, five showed some signs of consciousness. Three of those five showed the ability to deliberately respond to stimuli at bedside. Most amazingly though, one of the patients managed to answer a series of yes-or-no questions by altering his brain activity, as measured by a MRI machine.
The questions referred to the patient's family, and included queries like 'do you have any brothers?'. When the patient was asked 'is your father's name Alexander?' (it is), his brain assumed a configuration nearly identical to that of a conscious control subject saying 'yes'. Similarly, when asked 'is your father's name Thomas?', the MRI read brain activity identical to a control person's 'no' answer.
So far, wider communication remains impossible, although advances in brain implants may soon change that. However, as that technology enables more and more communication between the seemingly unconscious and the outside world, medicine and society will bump up against the problem of quickly defining consciousness for the sake of treatment, when any solid definition of the mind has eluded philosophers for millennia.
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